Crystal Reports Viewer works on one server, not another

I am having a problem with deploying my Visual Studio Project to a Windows 2012 Server running ASP.NET Framework 4.0.30319

The SAP Crystal Reports runtime engine for .NET framework (32 bit) is installed and shows as version 13.0.13.1597.

I have successfully deployed to a similar server (same framework, same runtime).  The only difference between the servers is that the bad server has the web root folder on E:\Web instead of under c:\inetpub\wwwroot.

I copied the aspnet_client from c:\inetpub\wwwroot to e:\web, but am still getting a bobj undefined error.

I am seeing some different behavior in Process Monitor - on the bad server, for some reason there is an attempt to open E:\web\aspnet_client\system_web\4_6_1069, but that folder does not exist.

I am not sure why this server is attempting to look in that folder and the good server isn't, or if this is even a problem.

Can someone help me diagnose/work around the bobj error?

Thanks,

-->Vince